{"id":1657,"date":"2011-10-15T22:27:26","date_gmt":"2011-10-15T22:27:26","guid":{"rendered":"http:\/\/www.ackc.org\/?p=1657"},"modified":"2011-10-15T22:27:26","modified_gmt":"2011-10-15T22:27:26","slug":"sutent-side-effects","status":"publish","type":"post","link":"https:\/\/www.ackc.org\/jayedit\/sutent-side-effects\/","title":{"rendered":"Sutent, Round 1: Dental Harpies, Wood Glue and Forrest Gump"},"content":{"rendered":"<p>I\u2019ve never been afraid of the dentist until now. Of course, that might be due to the fact that I did not always go to<img loading=\"lazy\" decoding=\"async\" class=\"alignright\" title=\"Sutent side effects sore gums\" src=\"http:\/\/2.bp.blogspot.com\/_zu5xVd55_XI\/SIve1N9EGWI\/AAAAAAAAB-Q\/7tKizedfOmo\/s400\/dentist14.jpg\" alt=\"Sutent side effects sore gums\" width=\"286\" height=\"400\" \/>thedentist as regularly as I should have when I was younger. When I did go in, the nurses would peer into my screwed-open mouth and I would hear the breath go out of them. I was always startled by the quasi-religious fervency of their reaction, the way they would hurl back on those rolling stools, as if punched in the sternum by the invisible hand of God, and fall to the floor speaking in tongues. After spraying Lysol or some other disinfectant into my mouth, most would eventually return, curette and cross in hand, to clean my teeth.<\/p>\n<p>As an adult I\u2019ve been better. It\u2019s difficult to drag my children into the dentist\u2019s office if I refuse to go myself. Kate already has a file under her bed tagged \u201cDad\u2019s Hypocrisies.\u201d By the time she is thirteen, it will require a filing cabinet. No reason to give her more ammunition than I have to.<\/p>\n<p>So you know it took some legitimate terror for me to call the dentist\u2019s office recently to cancel my appointment. However, I find that I am often spitting blood when I brush my teeth. A few of Sutent\u2019s side effects are sensitive gums, mouth sores and excessive bleeding. Together, they make a hat trick of dental hell. And that savage harpy my dentist has hired to serve as his hygienist has no compassion. She alternates between humming and lecturing me about poor flossing habits while slicing ravines in my gums.<\/p>\n<p>After discussing this with my oncology team, we all agreed that it would be wise to reschedule my teeth-cleaning appointment until I finished my first cycle of Sutent.<\/p>\n<p>Which, I would like to say, I have now done.<\/p>\n<p>All in all, the side effects have been quite manageable. I\u2019ve heard of some of the trials that others have undergone with Sutent. I\u2019ve received notes from fellow kidney cancer patients who have pointed out that in the last two weeks of taking the drug they have experienced fatigue so great that they couldn\u2019t get out of bed. Or Hand-Foot Syndrome so bad they couldn\u2019t walk. Nausea so bad they couldn\u2019t go far from a bathroom.<\/p>\n<p>I\u2019ve experienced a number of the side effects, but at a minimal level. While I do have some trouble with sensitive gums, I don\u2019t have mouth sores. While I have felt the effects of fatigue toward the end of the day, I\u2019ve never felt I couldn\u2019t put in a full day of work. I do experience nausea at times, but only a hint of it and never resulting in vomiting.<\/p>\n<p>The most significant side effects have been high blood pressure and loss of appetite. I have a prescription to deal with the high blood pressure, so no big deal. The loss of appetite is perhaps the most annoying. It is the result of simply not being hungry, but also the result of one other side effect \u2013 a complete loss of taste. Everything I eat tastes like wood glue. I was never a foodie, so there are worse side effects, but you know you\u2019ve entered black days when it\u2019s a chore to eat pizza. Some of you may remember my obsession with Chick-fil-a sandwiches whenever I went to Duke for a treatment. They opened one here in Crystal City and I went by the other day and I might as well have ordered a discarded toupee for lunch. It would have tasted about the same.<\/p>\n<p>I&#8217;ve flirted with Hand-Foot Syndrome, but the symptoms were largely brought on by my own stupidity. You can learn a little about Hand-Foot Syndrome at the ridiculously literal website <a title=\"Sutent chemotherapy care\" href=\"http:\/\/www.chemocare.com\/managing\/handfoot_syndrome.asp\" target=\"_blank\">ChemoCare.com<\/a>. It explains that exposure of your palms and soles of the feet to heat and friction causes drug leakage into your capillaries, resulting in redness, soreness and blisters. The site is pretty specific about taking steps to modify your \u201cnormal daily activities to reduce friction and heat exposure [their emphasis].\u201d Suggestions include:<\/p>\n<ul>\n<li>Avoid exposure of hands\/feet to hot water, such as taking long showers and washing dishes (Are you reading this, Dena?)<\/li>\n<li>Avoid activities that apply pressure on the palms of the hands or soles of the feet<\/li>\n<li>Avoid jogging, aerobics and long walks<\/li>\n<li>Avoid garden tools, household tools such as screwdrivers, and tasks that require squeezing the hands on hard surfaces<\/li>\n<li>Using knives to chop food may cause excessive friction (I assume their point here is that you should avoid it.)<\/li>\n<li>The list does not specifically advise against playing golf, but \u2026 perhaps I should\u2019ve taken the hint.<\/li>\n<\/ul>\n<p>Anybody who plays golf knows that most of the physical activity of the sport involves friction on the palms (mostly fingers, if you\u2019re any good, but I\u2019ll have to stick with palms) and the soles of the feet. Watch a golfer driving the ball off the tee. Check out the twisting motions of the feet, all the friction on the soles. Or consider the golf grip, the repeated friction of swinging the club. In short: If there were one activity that could be devised specifically to exacerbate Hand-Foot Syndrome, it would be golf. So, of course, I feel the need to step up and play more.<\/p>\n<p>The result? Friends and colleagues may or may not have noticed my newfound effort to make band aids a fashionable accessory. I went out and played golf on Monday and my hands are still blistered. It hurts to wash them, not only from the blisters but also from a general tingling\/burning when I use hot water or shave. People may have also noticed that they must walk a little slower when they are trying to talk to me, due to soreness in my feet. And, for good measure, the twisting of the knees that accompanies golf, when mixed with Sutent, results in some pretty sharp joint pain.<\/p>\n<p>As I\u2019ve said, though, these are relatively minor side effects compared to what others have gone through. So I think it\u2019s important to report this: I\u2019m doing great.<\/p>\n<p>And to my friends who are looking to start Sutent, the even better news is this: You are not as stupid as I am. You aren\u2019t likely to do the very things that the doctors tell you not to do. Don\u2019t take up clogging. Rock climbing may not be your best bet for weekend excitement. And stay the hell away from the golf course.<\/p>\n<p>As for me, though, I do stupid things. Ask Dena. I\u2019m Forrest Gump with a sand wedge. I have to tell you, though: I birdied a 502-yard hole this weekend, and that tends to soothe any blisters and put a little flavor back in my food. There\u2019s something to be said for maintaining control over your body, even if that means abusing it a little.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>There\u2019s something to be said for maintaining control over your body, even if that means abusing it a little.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[40,9,50],"class_list":["post-1657","post","type-post","status-publish","format-standard","hentry","category-blog","tag-chris-battle","tag-kidney-cancer","tag-sutent"],"_links":{"self":[{"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/posts\/1657","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/comments?post=1657"}],"version-history":[{"count":2,"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/posts\/1657\/revisions"}],"predecessor-version":[{"id":1659,"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/posts\/1657\/revisions\/1659"}],"wp:attachment":[{"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/media?parent=1657"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/categories?post=1657"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ackc.org\/jayedit\/wp-json\/wp\/v2\/tags?post=1657"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}